S100A6-BCL7A Gene Fusion FISH Probe
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Catalog: |
GFFP-S100A6/BCL7A-10548 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The S100A6-BCL7A Gene Fusion FISH Probecan detect the fusion of S100A6 and BCL7A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
S100A6-BCL7A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
BCL Tumor Suppressor 7A |
Gene Summary 1 |
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q24.31 |
Coordinates 1 |
This gene maps to 122459860-122499950 in GRCh37 coordinates. |
Gene Name 2 |
S100 Calcium Binding Protein A6 |
Gene Summary 2 |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q21.3 |
Coordinates 2 |
This gene maps to 153507075-153508717 in GRCh37 coordinates. |
Associated Diseases |
Thyroid Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-S100A6/BCL7A-10548-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-S100A6/BCL7A-10548-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-S100A6/BCL7A-10548-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-S100A6/BCL7A-10548-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-S100A6/BCL7A-10548-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-S100A6/BCL7A-10548-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-S100A6/BCL7A-10548-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-S100A6/BCL7A-10548-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-S100A6/BCL7A-10548-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-S100A6/BCL7A-10548-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-S100A6/BCL7A-10548-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-S100A6/BCL7A-10548-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-S100A6/BCL7A-10548-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-S100A6/BCL7A-10548-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-S100A6/BCL7A-10548-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-S100A6/BCL7A-10548-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-S100A6/BCL7A-10548-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-S100A6/BCL7A-10548-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-S100A6/BCL7A-10548-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-S100A6/BCL7A-10548-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-S100A6/BCL7A-10548-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-S100A6/BCL7A-10548-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-S100A6/BCL7A-10548-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-S100A6/BCL7A-10548-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-S100A6/BCL7A-10548-AQAQ |
467nm;467nm |
418nm;418nm |
|
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