S100A4-ELK3 Gene Fusion FISH Probe
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Catalog: |
GFFP-S100A4/ELK3-10549 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The S100A4-ELK3 Gene Fusion FISH Probecan detect the fusion of S100A4 and ELK3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
S100A4-ELK3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ELK3, ETS Transcription Factor |
Gene Summary 1 |
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q23.1 |
Coordinates 1 |
This gene maps to 96588206-96661606 in GRCh37 coordinates. |
Gene Name 2 |
S100 Calcium Binding Protein A4 |
Gene Summary 2 |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q21.3 |
Coordinates 2 |
This gene maps to 153516094-153518282 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-S100A4/ELK3-10549-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-S100A4/ELK3-10549-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-S100A4/ELK3-10549-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-S100A4/ELK3-10549-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-S100A4/ELK3-10549-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-S100A4/ELK3-10549-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-S100A4/ELK3-10549-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-S100A4/ELK3-10549-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-S100A4/ELK3-10549-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-S100A4/ELK3-10549-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-S100A4/ELK3-10549-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-S100A4/ELK3-10549-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-S100A4/ELK3-10549-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-S100A4/ELK3-10549-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-S100A4/ELK3-10549-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-S100A4/ELK3-10549-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-S100A4/ELK3-10549-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-S100A4/ELK3-10549-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-S100A4/ELK3-10549-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-S100A4/ELK3-10549-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-S100A4/ELK3-10549-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-S100A4/ELK3-10549-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-S100A4/ELK3-10549-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-S100A4/ELK3-10549-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-S100A4/ELK3-10549-AQAQ |
467nm;467nm |
418nm;418nm |
|
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