RUNX1-PROS1 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-RUNX1/PROS1-10223 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RUNX1-PROS1 Gene Fusion FISH Probecan detect the fusion of RUNX1 and PROS1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RUNX1-PROS1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Runt Related Transcription Factor 1 |
Gene Summary 1 |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 21 |
Locus 1 |
21q22.12 |
Coordinates 1 |
This gene maps to 36160097-36421595 in GRCh37 coordinates. |
Gene Name 2 |
Protein S |
Gene Summary 2 |
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q11.1 |
Coordinates 2 |
This gene maps to 93591880-93692934 in GRCh37 coordinates. |
Associated Diseases |
Colon Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RUNX1/PROS1-10223-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RUNX1/PROS1-10223-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RUNX1/PROS1-10223-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RUNX1/PROS1-10223-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RUNX1/PROS1-10223-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RUNX1/PROS1-10223-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RUNX1/PROS1-10223-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RUNX1/PROS1-10223-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RUNX1/PROS1-10223-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RUNX1/PROS1-10223-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RUNX1/PROS1-10223-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RUNX1/PROS1-10223-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RUNX1/PROS1-10223-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RUNX1/PROS1-10223-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RUNX1/PROS1-10223-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RUNX1/PROS1-10223-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RUNX1/PROS1-10223-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RUNX1/PROS1-10223-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RUNX1/PROS1-10223-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RUNX1/PROS1-10223-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RUNX1/PROS1-10223-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RUNX1/PROS1-10223-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RUNX1/PROS1-10223-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RUNX1/PROS1-10223-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RUNX1/PROS1-10223-AQAQ |
467nm;467nm |
418nm;418nm |
|
Other Products