RPL18-COL1A1 Gene Fusion FISH Probe
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Catalog: |
GFFP-RPL18/COL1A1-14521 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RPL18-COL1A1 Gene Fusion FISH Probecan detect the fusion of RPL18 and COL1A1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RPL18-COL1A1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Collagen Type I Alpha 1 Chain |
Gene Summary 1 |
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.33 |
Coordinates 1 |
This gene maps to 48261456-48279000 in GRCh37 coordinates. |
Gene Name 2 |
Ribosomal Protein L18 |
Gene Summary 2 |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19q13.33 |
Coordinates 2 |
This gene maps to 49118587-49122433 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RPL18/COL1A1-14521-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RPL18/COL1A1-14521-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RPL18/COL1A1-14521-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RPL18/COL1A1-14521-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RPL18/COL1A1-14521-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RPL18/COL1A1-14521-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RPL18/COL1A1-14521-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RPL18/COL1A1-14521-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RPL18/COL1A1-14521-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RPL18/COL1A1-14521-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RPL18/COL1A1-14521-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RPL18/COL1A1-14521-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RPL18/COL1A1-14521-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RPL18/COL1A1-14521-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RPL18/COL1A1-14521-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RPL18/COL1A1-14521-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RPL18/COL1A1-14521-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RPL18/COL1A1-14521-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RPL18/COL1A1-14521-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RPL18/COL1A1-14521-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RPL18/COL1A1-14521-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RPL18/COL1A1-14521-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RPL18/COL1A1-14521-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RPL18/COL1A1-14521-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RPL18/COL1A1-14521-AQAQ |
467nm;467nm |
418nm;418nm |
|
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