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RPL18-CFB Gene Fusion FISH Probe

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Catalog: GFFP-RPL18/CFB-14522
Classification: Gene Fusion FISH Probes
Description: The RPL18-CFB Gene Fusion FISH Probecan detect the fusion of RPL18 and CFB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RPL18-CFB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Complement Factor B
Gene Summary 1 This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 6_dbb_hap3
Locus 1 6p21.33
Coordinates 1 This gene maps to 3199308-3205449 in GRCh37 coordinates.
Gene Name 2 Ribosomal Protein L18
Gene Summary 2 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Chromosome 2 Chromosome19
Locus 2 19q13.33
Coordinates 2 This gene maps to 49118587-49122433 in GRCh37 coordinates.
Associated Diseases Head And Neck Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RPL18/CFB-14522-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RPL18/CFB-14522-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RPL18/CFB-14522-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RPL18/CFB-14522-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RPL18/CFB-14522-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RPL18/CFB-14522-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RPL18/CFB-14522-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RPL18/CFB-14522-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RPL18/CFB-14522-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RPL18/CFB-14522-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RPL18/CFB-14522-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RPL18/CFB-14522-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RPL18/CFB-14522-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RPL18/CFB-14522-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RPL18/CFB-14522-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RPL18/CFB-14522-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RPL18/CFB-14522-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RPL18/CFB-14522-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RPL18/CFB-14522-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RPL18/CFB-14522-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RPL18/CFB-14522-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RPL18/CFB-14522-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RPL18/CFB-14522-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RPL18/CFB-14522-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RPL18/CFB-14522-AQAQ 467nm;467nm 418nm;418nm

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