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ROR1-IL12RB2 Gene Fusion FISH Probe

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Catalog: GFFP-ROR1/IL12RB2-10353
Classification: Gene Fusion FISH Probes
Description: The ROR1-IL12RB2 Gene Fusion FISH Probecan detect the fusion of ROR1 and IL12RB2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ROR1-IL12RB2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Interleukin 12 Receptor Subunit Beta 2
Gene Summary 1 The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Chromosome 1 Chromosome 1
Locus 1 1p31.3
Coordinates 1 This gene maps to 67773046-67862583 in GRCh37 coordinates.
Gene Name 2 Receptor Tyrosine Kinase Like Orphan Receptor 1
Gene Summary 2 This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
Chromosome 2 Chromosome1
Locus 2 1p31.3
Coordinates 2 This gene maps to 64239689-64644707 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ROR1/IL12RB2-10353-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ROR1/IL12RB2-10353-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ROR1/IL12RB2-10353-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ROR1/IL12RB2-10353-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ROR1/IL12RB2-10353-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ROR1/IL12RB2-10353-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ROR1/IL12RB2-10353-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ROR1/IL12RB2-10353-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ROR1/IL12RB2-10353-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ROR1/IL12RB2-10353-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ROR1/IL12RB2-10353-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ROR1/IL12RB2-10353-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ROR1/IL12RB2-10353-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ROR1/IL12RB2-10353-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ROR1/IL12RB2-10353-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ROR1/IL12RB2-10353-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ROR1/IL12RB2-10353-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ROR1/IL12RB2-10353-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ROR1/IL12RB2-10353-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ROR1/IL12RB2-10353-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ROR1/IL12RB2-10353-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ROR1/IL12RB2-10353-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ROR1/IL12RB2-10353-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ROR1/IL12RB2-10353-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ROR1/IL12RB2-10353-AQAQ 467nm;467nm 418nm;418nm

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