RNF43-RARA Gene Fusion FISH Probe
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Catalog: |
GFFP-RNF43/RARA-10024 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RNF43-RARA Gene Fusion FISH Probecan detect the fusion of RNF43 and RARA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RNF43-RARA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Retinoic Acid Receptor Alpha |
Gene Summary 1 |
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.2 |
Coordinates 1 |
This gene maps to 38465422-38513895 in GRCh37 coordinates. |
Gene Name 2 |
Ring Finger Protein 43 |
Gene Summary 2 |
The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q22 |
Coordinates 2 |
This gene maps to 56431037-56494931 in GRCh37 coordinates. |
Associated Diseases |
Colon Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RNF43/RARA-10024-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RNF43/RARA-10024-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RNF43/RARA-10024-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RNF43/RARA-10024-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RNF43/RARA-10024-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RNF43/RARA-10024-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RNF43/RARA-10024-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RNF43/RARA-10024-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RNF43/RARA-10024-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RNF43/RARA-10024-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RNF43/RARA-10024-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RNF43/RARA-10024-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RNF43/RARA-10024-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RNF43/RARA-10024-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RNF43/RARA-10024-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RNF43/RARA-10024-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RNF43/RARA-10024-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RNF43/RARA-10024-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RNF43/RARA-10024-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RNF43/RARA-10024-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RNF43/RARA-10024-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RNF43/RARA-10024-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RNF43/RARA-10024-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RNF43/RARA-10024-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RNF43/RARA-10024-AQAQ |
467nm;467nm |
418nm;418nm |
|
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