RNF170-SFRP1 Gene Fusion FISH Probe
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Catalog: |
GFFP-RNF170/SFRP1-10062 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RNF170-SFRP1 Gene Fusion FISH Probecan detect the fusion of RNF170 and SFRP1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RNF170-SFRP1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Secreted Frizzled Related Protein 1 |
Gene Summary 1 |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8p11.21 |
Coordinates 1 |
This gene maps to 41119475-41166990 in GRCh37 coordinates. |
Gene Name 2 |
Ring Finger Protein 170 |
Gene Summary 2 |
This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8p11.21 |
Coordinates 2 |
This gene maps to 42704779-42751866 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RNF170/SFRP1-10062-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RNF170/SFRP1-10062-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RNF170/SFRP1-10062-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RNF170/SFRP1-10062-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RNF170/SFRP1-10062-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RNF170/SFRP1-10062-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RNF170/SFRP1-10062-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RNF170/SFRP1-10062-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RNF170/SFRP1-10062-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RNF170/SFRP1-10062-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RNF170/SFRP1-10062-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RNF170/SFRP1-10062-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RNF170/SFRP1-10062-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RNF170/SFRP1-10062-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RNF170/SFRP1-10062-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RNF170/SFRP1-10062-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RNF170/SFRP1-10062-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RNF170/SFRP1-10062-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RNF170/SFRP1-10062-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RNF170/SFRP1-10062-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RNF170/SFRP1-10062-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RNF170/SFRP1-10062-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RNF170/SFRP1-10062-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RNF170/SFRP1-10062-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RNF170/SFRP1-10062-AQAQ |
467nm;467nm |
418nm;418nm |
|
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