RNF144A-MSH2 Gene Fusion FISH Probe
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Catalog: |
GFFP-RNF144A/MSH2-10076 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RNF144A-MSH2 Gene Fusion FISH Probecan detect the fusion of RNF144A and MSH2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RNF144A-MSH2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
MutS Homolog 2 |
Gene Summary 1 |
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2p21-p16.3 |
Coordinates 1 |
This gene maps to 47630262-47710360 in GRCh37 coordinates. |
Gene Name 2 |
Ring Finger Protein 144A |
Gene Summary 2 |
This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2p25.1 |
Coordinates 2 |
This gene maps to 7057522-7184309 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RNF144A/MSH2-10076-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RNF144A/MSH2-10076-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RNF144A/MSH2-10076-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RNF144A/MSH2-10076-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RNF144A/MSH2-10076-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RNF144A/MSH2-10076-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RNF144A/MSH2-10076-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RNF144A/MSH2-10076-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RNF144A/MSH2-10076-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RNF144A/MSH2-10076-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RNF144A/MSH2-10076-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RNF144A/MSH2-10076-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RNF144A/MSH2-10076-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RNF144A/MSH2-10076-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RNF144A/MSH2-10076-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RNF144A/MSH2-10076-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RNF144A/MSH2-10076-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RNF144A/MSH2-10076-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RNF144A/MSH2-10076-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RNF144A/MSH2-10076-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RNF144A/MSH2-10076-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RNF144A/MSH2-10076-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RNF144A/MSH2-10076-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RNF144A/MSH2-10076-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RNF144A/MSH2-10076-AQAQ |
467nm;467nm |
418nm;418nm |
|
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