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RHOT1-FGFR1 Gene Fusion FISH Probe

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Catalog: GFFP-RHOT1/FGFR1-10127
Classification: Gene Fusion FISH Probes
Description: The RHOT1-FGFR1 Gene Fusion FISH Probecan detect the fusion of RHOT1 and FGFR1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RHOT1-FGFR1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Fibroblast Growth Factor Receptor 1
Gene Summary 1 The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 8
Locus 1 8p11.23
Coordinates 1 This gene maps to 38268655-38326352 in GRCh37 coordinates.
Gene Name 2 Ras Homolog Family Member T1
Gene Summary 2 The Ras Homolog Family Member T1 (RHOT1) gene is located on chr17 :30469472-30552746 at 17q11.2.
Chromosome 2 Chromosome17
Locus 2 17q11.2
Coordinates 2 This gene maps to 30469472-30552746 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RHOT1/FGFR1-10127-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RHOT1/FGFR1-10127-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RHOT1/FGFR1-10127-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RHOT1/FGFR1-10127-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RHOT1/FGFR1-10127-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RHOT1/FGFR1-10127-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RHOT1/FGFR1-10127-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RHOT1/FGFR1-10127-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RHOT1/FGFR1-10127-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RHOT1/FGFR1-10127-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RHOT1/FGFR1-10127-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RHOT1/FGFR1-10127-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RHOT1/FGFR1-10127-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RHOT1/FGFR1-10127-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RHOT1/FGFR1-10127-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RHOT1/FGFR1-10127-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RHOT1/FGFR1-10127-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RHOT1/FGFR1-10127-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RHOT1/FGFR1-10127-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RHOT1/FGFR1-10127-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RHOT1/FGFR1-10127-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RHOT1/FGFR1-10127-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RHOT1/FGFR1-10127-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RHOT1/FGFR1-10127-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RHOT1/FGFR1-10127-AQAQ 467nm;467nm 418nm;418nm

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