RGS6-NPAS3 Gene Fusion FISH Probe
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Catalog: |
GFFP-RGS6/NPAS3-10012 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RGS6-NPAS3 Gene Fusion FISH Probecan detect the fusion of RGS6 and NPAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RGS6-NPAS3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Regulator Of G Protein Signaling 6 |
Gene Summary 1 |
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q24.2 |
Coordinates 1 |
This gene maps to 72398816-73033238 in GRCh37 coordinates. |
Gene Name 2 |
Neuronal PAS Domain Protein 3 |
Gene Summary 2 |
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
Chromosome 2 |
Chromosome14 |
Locus 2 |
14q13.1 |
Coordinates 2 |
This gene maps to 33408458-34273382 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RGS6/NPAS3-10012-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RGS6/NPAS3-10012-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RGS6/NPAS3-10012-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RGS6/NPAS3-10012-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RGS6/NPAS3-10012-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RGS6/NPAS3-10012-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RGS6/NPAS3-10012-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RGS6/NPAS3-10012-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RGS6/NPAS3-10012-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RGS6/NPAS3-10012-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RGS6/NPAS3-10012-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RGS6/NPAS3-10012-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RGS6/NPAS3-10012-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RGS6/NPAS3-10012-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RGS6/NPAS3-10012-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RGS6/NPAS3-10012-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RGS6/NPAS3-10012-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RGS6/NPAS3-10012-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RGS6/NPAS3-10012-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RGS6/NPAS3-10012-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RGS6/NPAS3-10012-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RGS6/NPAS3-10012-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RGS6/NPAS3-10012-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RGS6/NPAS3-10012-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RGS6/NPAS3-10012-AQAQ |
467nm;467nm |
418nm;418nm |
|
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