RGS12-USP2 Gene Fusion FISH Probe
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Catalog: |
GFFP-RGS12/USP2-10161 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RGS12-USP2 Gene Fusion FISH Probecan detect the fusion of RGS12 and USP2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RGS12-USP2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Regulator Of G Protein Signaling 12 |
Gene Summary 1 |
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4p16.3 |
Coordinates 1 |
This gene maps to 3315873-3441640 in GRCh37 coordinates. |
Gene Name 2 |
Ubiquitin Specific Peptidase 2 |
Gene Summary 2 |
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q23.3 |
Coordinates 2 |
This gene maps to 119225924-119252436 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RGS12/USP2-10161-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RGS12/USP2-10161-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RGS12/USP2-10161-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RGS12/USP2-10161-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RGS12/USP2-10161-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RGS12/USP2-10161-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RGS12/USP2-10161-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RGS12/USP2-10161-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RGS12/USP2-10161-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RGS12/USP2-10161-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RGS12/USP2-10161-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RGS12/USP2-10161-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RGS12/USP2-10161-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RGS12/USP2-10161-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RGS12/USP2-10161-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RGS12/USP2-10161-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RGS12/USP2-10161-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RGS12/USP2-10161-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RGS12/USP2-10161-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RGS12/USP2-10161-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RGS12/USP2-10161-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RGS12/USP2-10161-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RGS12/USP2-10161-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RGS12/USP2-10161-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RGS12/USP2-10161-AQAQ |
467nm;467nm |
418nm;418nm |
|
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