RB1-MED4 Gene Fusion FISH Probe
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Catalog: |
GFFP-RB1/MED4-15495 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RB1-MED4 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RB1-MED4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RB Transcriptional Corepressor 1 |
Gene Summary 1 |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 13 |
Locus 1 |
13q14.2 |
Coordinates 1 |
This gene maps to 48877882-49056026in GRCh37 coordinates. |
Gene Name 2 |
Mediator Complex Subunit 4 |
Gene Summary 2 |
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
Chromosome 2 |
Chromosome13 |
Locus 2 |
13q14.2 |
Coordinates 2 |
This gene maps to 48650091-48669240 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma; Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RB1/MED4-15495-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RB1/MED4-15495-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RB1/MED4-15495-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RB1/MED4-15495-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RB1/MED4-15495-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RB1/MED4-15495-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RB1/MED4-15495-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RB1/MED4-15495-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RB1/MED4-15495-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RB1/MED4-15495-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RB1/MED4-15495-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RB1/MED4-15495-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RB1/MED4-15495-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RB1/MED4-15495-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RB1/MED4-15495-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RB1/MED4-15495-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RB1/MED4-15495-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RB1/MED4-15495-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RB1/MED4-15495-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RB1/MED4-15495-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RB1/MED4-15495-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RB1/MED4-15495-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RB1/MED4-15495-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RB1/MED4-15495-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RB1/MED4-15495-AQAQ |
467nm;467nm |
418nm;418nm |
|
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