RB1-CLEC2B Gene Fusion FISH Probe
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Catalog: |
GFFP-RB1/CLEC2B-09987 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RB1-CLEC2B Gene Fusion FISH Probecan detect the fusion of RB1 and CLEC2B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RB1-CLEC2B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RB Transcriptional Corepressor 1 |
Gene Summary 1 |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 13 |
Locus 1 |
13q14.2 |
Coordinates 1 |
This gene maps to 48877882-49056026 in GRCh37 coordinates. |
Gene Name 2 |
C-type Lectin Domain Family 2 Member B |
Gene Summary 2 |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12p13.31 |
Coordinates 2 |
This gene maps to 10004967-10022458 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RB1/CLEC2B-09987-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RB1/CLEC2B-09987-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RB1/CLEC2B-09987-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RB1/CLEC2B-09987-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RB1/CLEC2B-09987-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RB1/CLEC2B-09987-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RB1/CLEC2B-09987-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RB1/CLEC2B-09987-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RB1/CLEC2B-09987-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RB1/CLEC2B-09987-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RB1/CLEC2B-09987-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RB1/CLEC2B-09987-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RB1/CLEC2B-09987-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RB1/CLEC2B-09987-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RB1/CLEC2B-09987-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RB1/CLEC2B-09987-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RB1/CLEC2B-09987-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RB1/CLEC2B-09987-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RB1/CLEC2B-09987-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RB1/CLEC2B-09987-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RB1/CLEC2B-09987-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RB1/CLEC2B-09987-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RB1/CLEC2B-09987-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RB1/CLEC2B-09987-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RB1/CLEC2B-09987-AQAQ |
467nm;467nm |
418nm;418nm |
|
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