RASSF5-IKBKE Gene Fusion FISH Probe
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Catalog: |
GFFP-RASSF5/IKBKE-14503 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RASSF5-IKBKE Gene Fusion FISH Probecan detect the fusion of RASSF5 and IKBKE genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RASSF5-IKBKE Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon |
Gene Summary 1 |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1q32.1 |
Coordinates 1 |
This gene maps to 206643585-206670223 in GRCh37 coordinates. |
Gene Name 2 |
Ras Association Domain Family Member 5 |
Gene Summary 2 |
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q32.1 |
Coordinates 2 |
This gene maps to 206680878-206762616 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RASSF5/IKBKE-14503-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RASSF5/IKBKE-14503-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RASSF5/IKBKE-14503-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RASSF5/IKBKE-14503-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RASSF5/IKBKE-14503-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RASSF5/IKBKE-14503-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RASSF5/IKBKE-14503-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RASSF5/IKBKE-14503-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RASSF5/IKBKE-14503-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RASSF5/IKBKE-14503-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RASSF5/IKBKE-14503-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RASSF5/IKBKE-14503-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RASSF5/IKBKE-14503-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RASSF5/IKBKE-14503-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RASSF5/IKBKE-14503-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RASSF5/IKBKE-14503-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RASSF5/IKBKE-14503-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RASSF5/IKBKE-14503-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RASSF5/IKBKE-14503-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RASSF5/IKBKE-14503-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RASSF5/IKBKE-14503-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RASSF5/IKBKE-14503-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RASSF5/IKBKE-14503-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RASSF5/IKBKE-14503-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RASSF5/IKBKE-14503-AQAQ |
467nm;467nm |
418nm;418nm |
|
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