RAP1B-SCYL2 Gene Fusion FISH Probe
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Catalog: |
GFFP-RAP1B/SCYL2-09753 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RAP1B-SCYL2 Gene Fusion FISH Probecan detect the fusion of RAP1B and SCYL2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RAP1B-SCYL2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RAP1B, Member Of RAS Oncogene Family |
Gene Summary 1 |
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q15 |
Coordinates 1 |
This gene maps to 69004651-69054374 in GRCh37 coordinates. |
Gene Name 2 |
SCY1 Like Pseudokinase 2 |
Gene Summary 2 |
The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q23.1 |
Coordinates 2 |
This gene maps to 100661548-100733914 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RAP1B/SCYL2-09753-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RAP1B/SCYL2-09753-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RAP1B/SCYL2-09753-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RAP1B/SCYL2-09753-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RAP1B/SCYL2-09753-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RAP1B/SCYL2-09753-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RAP1B/SCYL2-09753-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RAP1B/SCYL2-09753-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RAP1B/SCYL2-09753-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RAP1B/SCYL2-09753-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RAP1B/SCYL2-09753-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RAP1B/SCYL2-09753-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RAP1B/SCYL2-09753-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RAP1B/SCYL2-09753-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RAP1B/SCYL2-09753-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RAP1B/SCYL2-09753-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RAP1B/SCYL2-09753-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RAP1B/SCYL2-09753-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RAP1B/SCYL2-09753-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RAP1B/SCYL2-09753-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RAP1B/SCYL2-09753-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RAP1B/SCYL2-09753-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RAP1B/SCYL2-09753-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RAP1B/SCYL2-09753-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RAP1B/SCYL2-09753-AQAQ |
467nm;467nm |
418nm;418nm |
|
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