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RALGAPB-CBFA2T2 Gene Fusion FISH Probe

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Catalog: GFFP-RALGAPB/CBFA2T2-14483
Classification: Gene Fusion FISH Probes
Description: The RALGAPB-CBFA2T2 Gene Fusion FISH Probecan detect the fusion of RALGAPB and CBFA2T2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RALGAPB-CBFA2T2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 CBFA2/RUNX1 Translocation Partner 2
Gene Summary 1 In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 20
Locus 1 20q11.21-q11.22
Coordinates 1 This gene maps to 32077927-32237837 in GRCh37 coordinates.
Gene Name 2 Ral GTPase Activating Protein Non-catalytic Beta Subunit
Gene Summary 2 The Ral GTPase Activating Protein Non-catalytic Beta Subunit (RALGAPB) gene is located on chr20 :37101485-37207504 at 20q11.23.
Chromosome 2 Chromosome20
Locus 2 20q11.23
Coordinates 2 This gene maps to 37101485-37207504 in GRCh37 coordinates.
Associated Diseases Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RALGAPB/CBFA2T2-14483-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RALGAPB/CBFA2T2-14483-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RALGAPB/CBFA2T2-14483-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RALGAPB/CBFA2T2-14483-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RALGAPB/CBFA2T2-14483-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RALGAPB/CBFA2T2-14483-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RALGAPB/CBFA2T2-14483-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RALGAPB/CBFA2T2-14483-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RALGAPB/CBFA2T2-14483-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RALGAPB/CBFA2T2-14483-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RALGAPB/CBFA2T2-14483-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RALGAPB/CBFA2T2-14483-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RALGAPB/CBFA2T2-14483-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RALGAPB/CBFA2T2-14483-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RALGAPB/CBFA2T2-14483-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RALGAPB/CBFA2T2-14483-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RALGAPB/CBFA2T2-14483-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RALGAPB/CBFA2T2-14483-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RALGAPB/CBFA2T2-14483-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RALGAPB/CBFA2T2-14483-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RALGAPB/CBFA2T2-14483-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RALGAPB/CBFA2T2-14483-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RALGAPB/CBFA2T2-14483-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RALGAPB/CBFA2T2-14483-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RALGAPB/CBFA2T2-14483-AQAQ 467nm;467nm 418nm;418nm

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