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RAF1-TMEM40 Gene Fusion FISH Probe

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Catalog: GFFP-RAF1/TMEM40-15482
Classification: Gene Fusion FISH Probes
Description: The RAF1-TMEM40 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAF1-TMEM40 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Raf-1 Proto-oncogene, Serine/threonine Kinase
Gene Summary 1 This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 3
Locus 1 3p25.2
Coordinates 1 This gene maps to 12625099-12705700in GRCh37 coordinates.
Gene Name 2 Transmembrane Protein 40
Gene Summary 2 The Transmembrane Protein 40 (TMEM40) gene is located on chr3 :12775391-12800808 at 3p25.2.
Chromosome 2 Chromosome3
Locus 2 3p25.2
Coordinates 2 This gene maps to 12775391-12800808 in GRCh37 coordinates.
Associated Diseases Testicular Germ Cell Tumors; Pancreatic Adenocarcinoma; Kidney Renal Clear Cell Carcinoma; Adrenocortical Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAF1/TMEM40-15482-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAF1/TMEM40-15482-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAF1/TMEM40-15482-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAF1/TMEM40-15482-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAF1/TMEM40-15482-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAF1/TMEM40-15482-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAF1/TMEM40-15482-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAF1/TMEM40-15482-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAF1/TMEM40-15482-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAF1/TMEM40-15482-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAF1/TMEM40-15482-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAF1/TMEM40-15482-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAF1/TMEM40-15482-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAF1/TMEM40-15482-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAF1/TMEM40-15482-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAF1/TMEM40-15482-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAF1/TMEM40-15482-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAF1/TMEM40-15482-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAF1/TMEM40-15482-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAF1/TMEM40-15482-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAF1/TMEM40-15482-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAF1/TMEM40-15482-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAF1/TMEM40-15482-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAF1/TMEM40-15482-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAF1/TMEM40-15482-AQAQ 467nm;467nm 418nm;418nm

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