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RAB8A-PLVAP Gene Fusion FISH Probe

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Catalog: GFFP-RAB8A/PLVAP-09846
Classification: Gene Fusion FISH Probes
Description: The RAB8A-PLVAP Gene Fusion FISH Probecan detect the fusion of RAB8A and PLVAP genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAB8A-PLVAP Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 RAB8A, Member RAS Oncogene Family
Gene Summary 1 The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 19
Locus 1 19p13.11
Coordinates 1 This gene maps to 16222489-16244445 in GRCh37 coordinates.
Gene Name 2 Plasmalemma Vesicle Associated Protein
Gene Summary 2 The Plasmalemma Vesicle Associated Protein (PLVAP) gene is located on chr19 :17462263-17488137 at 19p13.11.
Chromosome 2 Chromosome19
Locus 2 19p13.11
Coordinates 2 This gene maps to 17462263-17488137 in GRCh37 coordinates.
Associated Diseases Adrenocortical Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAB8A/PLVAP-09846-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAB8A/PLVAP-09846-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAB8A/PLVAP-09846-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAB8A/PLVAP-09846-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAB8A/PLVAP-09846-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAB8A/PLVAP-09846-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAB8A/PLVAP-09846-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAB8A/PLVAP-09846-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAB8A/PLVAP-09846-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAB8A/PLVAP-09846-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAB8A/PLVAP-09846-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAB8A/PLVAP-09846-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAB8A/PLVAP-09846-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAB8A/PLVAP-09846-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAB8A/PLVAP-09846-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAB8A/PLVAP-09846-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAB8A/PLVAP-09846-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAB8A/PLVAP-09846-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAB8A/PLVAP-09846-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAB8A/PLVAP-09846-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAB8A/PLVAP-09846-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAB8A/PLVAP-09846-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAB8A/PLVAP-09846-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAB8A/PLVAP-09846-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAB8A/PLVAP-09846-AQAQ 467nm;467nm 418nm;418nm

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