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RAB6A-MRPL48 Gene Fusion FISH Probe

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Catalog: GFFP-RAB6A/MRPL48-09852
Classification: Gene Fusion FISH Probes
Description: The RAB6A-MRPL48 Gene Fusion FISH Probecan detect the fusion of RAB6A and MRPL48 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAB6A-MRPL48 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 RAB6A, Member RAS Oncogene Family
Gene Summary 1 This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Chromosome 1 Chromosome 11
Locus 1 11q13.4
Coordinates 1 This gene maps to 73386682-73472201 in GRCh37 coordinates.
Gene Name 2 Mitochondrial Ribosomal Protein L48
Gene Summary 2 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
Chromosome 2 Chromosome11
Locus 2 11q13.4
Coordinates 2 This gene maps to 73498916-73575656 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAB6A/MRPL48-09852-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAB6A/MRPL48-09852-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAB6A/MRPL48-09852-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAB6A/MRPL48-09852-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAB6A/MRPL48-09852-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAB6A/MRPL48-09852-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAB6A/MRPL48-09852-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAB6A/MRPL48-09852-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAB6A/MRPL48-09852-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAB6A/MRPL48-09852-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAB6A/MRPL48-09852-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAB6A/MRPL48-09852-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAB6A/MRPL48-09852-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAB6A/MRPL48-09852-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAB6A/MRPL48-09852-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAB6A/MRPL48-09852-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAB6A/MRPL48-09852-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAB6A/MRPL48-09852-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAB6A/MRPL48-09852-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAB6A/MRPL48-09852-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAB6A/MRPL48-09852-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAB6A/MRPL48-09852-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAB6A/MRPL48-09852-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAB6A/MRPL48-09852-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAB6A/MRPL48-09852-AQAQ 467nm;467nm 418nm;418nm

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