RAB6A-MICA Gene Fusion FISH Probe
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Catalog: |
GFFP-RAB6A/MICA-09853 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RAB6A-MICA Gene Fusion FISH Probecan detect the fusion of RAB6A and MICA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RAB6A-MICA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RAB6A, Member RAS Oncogene Family |
Gene Summary 1 |
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.4 |
Coordinates 1 |
This gene maps to 73386682-73472201 in GRCh37 coordinates. |
Gene Name 2 |
MHC Class I Polypeptide-related Sequence A |
Gene Summary 2 |
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Chromosome 2 |
Chromosome6_qbl_hap6 |
Locus 2 |
6p21.33 |
Coordinates 2 |
This gene maps to 2661006-2676580 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RAB6A/MICA-09853-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RAB6A/MICA-09853-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RAB6A/MICA-09853-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RAB6A/MICA-09853-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RAB6A/MICA-09853-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RAB6A/MICA-09853-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RAB6A/MICA-09853-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RAB6A/MICA-09853-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RAB6A/MICA-09853-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RAB6A/MICA-09853-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RAB6A/MICA-09853-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RAB6A/MICA-09853-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RAB6A/MICA-09853-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RAB6A/MICA-09853-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RAB6A/MICA-09853-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RAB6A/MICA-09853-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RAB6A/MICA-09853-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RAB6A/MICA-09853-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RAB6A/MICA-09853-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RAB6A/MICA-09853-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RAB6A/MICA-09853-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RAB6A/MICA-09853-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RAB6A/MICA-09853-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RAB6A/MICA-09853-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RAB6A/MICA-09853-AQAQ |
467nm;467nm |
418nm;418nm |
|
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