RAB6A-HIST1H2AC Gene Fusion FISH Probe
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Catalog: |
GFFP-RAB6A/HIST1H2AC-09541 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RAB6A-HIST1H2AC Gene Fusion FISH Probecan detect the fusion of RAB6A and HIST1H2AC genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RAB6A-HIST1H2AC Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RAB6A, Member RAS Oncogene Family |
Gene Summary 1 |
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.4 |
Coordinates 1 |
This gene maps to 73386682-73472201 in GRCh37 coordinates. |
Gene Name 2 |
Histone Cluster 1 H2A Family Member C |
Gene Summary 2 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] |
Chromosome 2 |
Chromosome6 |
Locus 2 |
6p22.2 |
Coordinates 2 |
This gene maps to 26124372-26124918 in GRCh37 coordinates. |
Associated Diseases |
Stomach Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RAB6A/HIST1H2AC-09541-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RAB6A/HIST1H2AC-09541-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RAB6A/HIST1H2AC-09541-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RAB6A/HIST1H2AC-09541-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RAB6A/HIST1H2AC-09541-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RAB6A/HIST1H2AC-09541-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RAB6A/HIST1H2AC-09541-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RAB6A/HIST1H2AC-09541-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RAB6A/HIST1H2AC-09541-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RAB6A/HIST1H2AC-09541-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RAB6A/HIST1H2AC-09541-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RAB6A/HIST1H2AC-09541-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RAB6A/HIST1H2AC-09541-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RAB6A/HIST1H2AC-09541-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RAB6A/HIST1H2AC-09541-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RAB6A/HIST1H2AC-09541-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RAB6A/HIST1H2AC-09541-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RAB6A/HIST1H2AC-09541-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RAB6A/HIST1H2AC-09541-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RAB6A/HIST1H2AC-09541-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RAB6A/HIST1H2AC-09541-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RAB6A/HIST1H2AC-09541-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RAB6A/HIST1H2AC-09541-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RAB6A/HIST1H2AC-09541-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RAB6A/HIST1H2AC-09541-AQAQ |
467nm;467nm |
418nm;418nm |
|
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