RAB4B-FBXL12 Gene Fusion FISH Probe
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Catalog: |
GFFP-RAB4B/FBXL12-09546 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RAB4B-FBXL12 Gene Fusion FISH Probecan detect the fusion of RAB4B and FBXL12 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RAB4B-FBXL12 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
RAB4B, Member RAS Oncogene Family |
Gene Summary 1 |
RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19q13.2 |
Coordinates 1 |
This gene maps to 41284123-41302849 in GRCh37 coordinates. |
Gene Name 2 |
F-box And Leucine Rich Repeat Protein 12 |
Gene Summary 2 |
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.2 |
Coordinates 2 |
This gene maps to 9920942-9929731 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-RAB4B/FBXL12-09546-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RAB4B/FBXL12-09546-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RAB4B/FBXL12-09546-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RAB4B/FBXL12-09546-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RAB4B/FBXL12-09546-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RAB4B/FBXL12-09546-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RAB4B/FBXL12-09546-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RAB4B/FBXL12-09546-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RAB4B/FBXL12-09546-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RAB4B/FBXL12-09546-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RAB4B/FBXL12-09546-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RAB4B/FBXL12-09546-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RAB4B/FBXL12-09546-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RAB4B/FBXL12-09546-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RAB4B/FBXL12-09546-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RAB4B/FBXL12-09546-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RAB4B/FBXL12-09546-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RAB4B/FBXL12-09546-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RAB4B/FBXL12-09546-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RAB4B/FBXL12-09546-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RAB4B/FBXL12-09546-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RAB4B/FBXL12-09546-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RAB4B/FBXL12-09546-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RAB4B/FBXL12-09546-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RAB4B/FBXL12-09546-AQAQ |
467nm;467nm |
418nm;418nm |
|
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