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| Catalog: | GFFP-PXK/FLNB-09635 |
| Classification: | Gene Fusion FISH Probes |
| Description: | The PXK-FLNB Gene Fusion FISH Probecan detect the fusion of PXK and FLNB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Application: | PXK-FLNB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | 7-10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name 1 | Filamin B |
| Gene Summary 1 | This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
| Chromosome 1 | Chromosome 3 |
| Locus 1 | 3p14.3 |
| Coordinates 1 | This gene maps to 57994126-58157982 in GRCh37 coordinates. |
| Gene Name 2 | PX Domain Containing Serine/threonine Kinase Like |
| Gene Summary 2 | This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| Chromosome 2 | Chromosome3 |
| Locus 2 | 3p14.3 |
| Coordinates 2 | This gene maps to 58318616-58410878 in GRCh37 coordinates. |
| Associated Diseases | Liver Hepatocellular Carcinoma |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | RE; RE | GFFP-PXK/FLNB-09635-RERE | 599nm;599nm | 580nm;580nm | |
| 2 | RE; OR | GFFP-PXK/FLNB-09635-REOR | 599nm;573nm | 580nm;548nm | |
| 3 | RE; GO | GFFP-PXK/FLNB-09635-REGO | 599nm;551nm | 580nm;525nm | |
| 4 | RE; GR | GFFP-PXK/FLNB-09635-REGR | 599nm;515nm | 580nm;491nm | |
| 5 | RE; AQ | GFFP-PXK/FLNB-09635-REAQ | 599nm;467nm | 580nm;418nm | |
| 6 | OR; RE | GFFP-PXK/FLNB-09635-ORRE | 573nm;599nm | 548nm;580nm | |
| 7 | OR; OR | GFFP-PXK/FLNB-09635-OROR | 573nm;573nm | 548nm;548nm | |
| 8 | OR; GO | GFFP-PXK/FLNB-09635-ORGO | 573nm;551nm | 548nm;525nm | |
| 9 | OR; GR | GFFP-PXK/FLNB-09635-ORGR | 573nm;515nm | 548nm;491nm | |
| 10 | OR; AQ | GFFP-PXK/FLNB-09635-ORAQ | 573nm;467nm | 548nm;418nm | |
| 11 | GO; RE | GFFP-PXK/FLNB-09635-GORE | 551nm;599nm | 525nm;580nm | |
| 12 | GO; OR | GFFP-PXK/FLNB-09635-GOOR | 551nm;573nm | 525nm;548nm | |
| 13 | GO; GO | GFFP-PXK/FLNB-09635-GOGO | 551nm;551nm | 525nm;525nm | |
| 14 | GO; GR | GFFP-PXK/FLNB-09635-GOGR | 551nm;515nm | 525nm;491nm | |
| 15 | GO; AQ | GFFP-PXK/FLNB-09635-GOAQ | 551nm;467nm | 525nm;418nm | |
| 16 | GR; RE | GFFP-PXK/FLNB-09635-GRRE | 515nm;599nm | 491nm;580nm | |
| 17 | GR; OR | GFFP-PXK/FLNB-09635-GROR | 515nm;573nm | 491nm;548nm | |
| 18 | GR; GO | GFFP-PXK/FLNB-09635-GRGO | 515nm;551nm | 491nm;525nm | |
| 19 | GR; GR | GFFP-PXK/FLNB-09635-GRGR | 515nm;515nm | 491nm;491nm | |
| 20 | GR; AQ | GFFP-PXK/FLNB-09635-GRAQ | 515nm;467nm | 491nm;418nm | |
| 21 | AQ; RE | GFFP-PXK/FLNB-09635-AQRE | 467nm;599nm | 418nm;580nm | |
| 22 | AQ; OR | GFFP-PXK/FLNB-09635-AQOR | 467nm;573nm | 418nm;548nm | |
| 23 | AQ; GO | GFFP-PXK/FLNB-09635-AQGO | 467nm;551nm | 418nm;525nm | |
| 24 | AQ; GR | GFFP-PXK/FLNB-09635-AQGR | 467nm;515nm | 418nm;491nm | |
| 25 | AQ; AQ | GFFP-PXK/FLNB-09635-AQAQ | 467nm;467nm | 418nm;418nm |
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