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PTRH2-PEX5L Gene Fusion FISH Probe

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Catalog: GFFP-PTRH2/PEX5L-09660
Classification: Gene Fusion FISH Probes
Description: The PTRH2-PEX5L Gene Fusion FISH Probecan detect the fusion of PTRH2 and PEX5L genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PTRH2-PEX5L Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Peroxisomal Biogenesis Factor 5 Like
Gene Summary 1 The Peroxisomal Biogenesis Factor 5 Like (PEX5L) gene is located on chr3 :179518049-179754517 at 3q26.33.
Chromosome 1 Chromosome 3
Locus 1 3q26.33
Coordinates 1 This gene maps to 179518049-179754517 in GRCh37 coordinates.
Gene Name 2 Peptidyl-tRNA Hydrolase 2
Gene Summary 2 The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos. After loss of cell attachment to the ECM, this protein is phosphorylated, is released from the mitochondria into the cytosol, and promotes caspase-independent apoptosis through interactions with transcriptional regulators. This gene has been implicated in the development and progression of tumors, and mutations in this gene have been associated with an infantile multisystem neurologic, endocrine, and pancreatic disease (INMEPD) characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency (PMID: 25574476). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Chromosome 2 Chromosome17
Locus 2 17q23.1
Coordinates 2 This gene maps to 57774666-57784856 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PTRH2/PEX5L-09660-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PTRH2/PEX5L-09660-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PTRH2/PEX5L-09660-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PTRH2/PEX5L-09660-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PTRH2/PEX5L-09660-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PTRH2/PEX5L-09660-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PTRH2/PEX5L-09660-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PTRH2/PEX5L-09660-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PTRH2/PEX5L-09660-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PTRH2/PEX5L-09660-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PTRH2/PEX5L-09660-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PTRH2/PEX5L-09660-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PTRH2/PEX5L-09660-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PTRH2/PEX5L-09660-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PTRH2/PEX5L-09660-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PTRH2/PEX5L-09660-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PTRH2/PEX5L-09660-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PTRH2/PEX5L-09660-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PTRH2/PEX5L-09660-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PTRH2/PEX5L-09660-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PTRH2/PEX5L-09660-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PTRH2/PEX5L-09660-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PTRH2/PEX5L-09660-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PTRH2/PEX5L-09660-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PTRH2/PEX5L-09660-AQAQ 467nm;467nm 418nm;418nm

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