PTPRS-MBD3 Gene Fusion FISH Probe
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Catalog: |
GFFP-PTPRS/MBD3-09671 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PTPRS-MBD3 Gene Fusion FISH Probecan detect the fusion of PTPRS and MBD3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PTPRS-MBD3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Protein Tyrosine Phosphatase, Receptor Type S |
Gene Summary 1 |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.3 |
Coordinates 1 |
This gene maps to 5205518-5340814 in GRCh37 coordinates. |
Gene Name 2 |
Methyl-CpG Binding Domain Protein 3 |
Gene Summary 2 |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.3 |
Coordinates 2 |
This gene maps to 1576677-1592652 in GRCh37 coordinates. |
Associated Diseases |
Esophageal Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PTPRS/MBD3-09671-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PTPRS/MBD3-09671-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PTPRS/MBD3-09671-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PTPRS/MBD3-09671-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PTPRS/MBD3-09671-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PTPRS/MBD3-09671-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PTPRS/MBD3-09671-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PTPRS/MBD3-09671-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PTPRS/MBD3-09671-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PTPRS/MBD3-09671-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PTPRS/MBD3-09671-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PTPRS/MBD3-09671-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PTPRS/MBD3-09671-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PTPRS/MBD3-09671-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PTPRS/MBD3-09671-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PTPRS/MBD3-09671-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PTPRS/MBD3-09671-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PTPRS/MBD3-09671-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PTPRS/MBD3-09671-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PTPRS/MBD3-09671-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PTPRS/MBD3-09671-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PTPRS/MBD3-09671-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PTPRS/MBD3-09671-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PTPRS/MBD3-09671-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PTPRS/MBD3-09671-AQAQ |
467nm;467nm |
418nm;418nm |
|
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