PTPRS-ANGPTL4 Gene Fusion FISH Probe
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Catalog: |
GFFP-PTPRS/ANGPTL4-09673 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PTPRS-ANGPTL4 Gene Fusion FISH Probecan detect the fusion of PTPRS and ANGPTL4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PTPRS-ANGPTL4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Protein Tyrosine Phosphatase, Receptor Type S |
Gene Summary 1 |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.3 |
Coordinates 1 |
This gene maps to 5205518-5340814 in GRCh37 coordinates. |
Gene Name 2 |
Angiopoietin Like 4 |
Gene Summary 2 |
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.2 |
Coordinates 2 |
This gene maps to 8429010-8439257 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PTPRS/ANGPTL4-09673-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PTPRS/ANGPTL4-09673-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PTPRS/ANGPTL4-09673-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PTPRS/ANGPTL4-09673-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PTPRS/ANGPTL4-09673-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PTPRS/ANGPTL4-09673-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PTPRS/ANGPTL4-09673-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PTPRS/ANGPTL4-09673-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PTPRS/ANGPTL4-09673-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PTPRS/ANGPTL4-09673-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PTPRS/ANGPTL4-09673-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PTPRS/ANGPTL4-09673-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PTPRS/ANGPTL4-09673-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PTPRS/ANGPTL4-09673-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PTPRS/ANGPTL4-09673-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PTPRS/ANGPTL4-09673-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PTPRS/ANGPTL4-09673-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PTPRS/ANGPTL4-09673-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PTPRS/ANGPTL4-09673-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PTPRS/ANGPTL4-09673-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PTPRS/ANGPTL4-09673-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PTPRS/ANGPTL4-09673-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PTPRS/ANGPTL4-09673-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PTPRS/ANGPTL4-09673-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PTPRS/ANGPTL4-09673-AQAQ |
467nm;467nm |
418nm;418nm |
|
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