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PTPN1-P2RX4 Gene Fusion FISH Probe

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Catalog: GFFP-PTPN1/P2RX4-14459
Classification: Gene Fusion FISH Probes
Description: The PTPN1-P2RX4 Gene Fusion FISH Probecan detect the fusion of PTPN1 and P2RX4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PTPN1-P2RX4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Purinergic Receptor P2X 4
Gene Summary 1 The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]
Chromosome 1 Chromosome 12
Locus 1 12q24.31
Coordinates 1 This gene maps to 121647663-121671909 in GRCh37 coordinates.
Gene Name 2 Protein Tyrosine Phosphatase, Non-receptor Type 1
Gene Summary 2 The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Chromosome 2 Chromosome20
Locus 2 20q13.13
Coordinates 2 This gene maps to 49126890-49201086 in GRCh37 coordinates.
Associated Diseases Head And Neck Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PTPN1/P2RX4-14459-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PTPN1/P2RX4-14459-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PTPN1/P2RX4-14459-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PTPN1/P2RX4-14459-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PTPN1/P2RX4-14459-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PTPN1/P2RX4-14459-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PTPN1/P2RX4-14459-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PTPN1/P2RX4-14459-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PTPN1/P2RX4-14459-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PTPN1/P2RX4-14459-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PTPN1/P2RX4-14459-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PTPN1/P2RX4-14459-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PTPN1/P2RX4-14459-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PTPN1/P2RX4-14459-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PTPN1/P2RX4-14459-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PTPN1/P2RX4-14459-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PTPN1/P2RX4-14459-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PTPN1/P2RX4-14459-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PTPN1/P2RX4-14459-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PTPN1/P2RX4-14459-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PTPN1/P2RX4-14459-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PTPN1/P2RX4-14459-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PTPN1/P2RX4-14459-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PTPN1/P2RX4-14459-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PTPN1/P2RX4-14459-AQAQ 467nm;467nm 418nm;418nm

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