PTCH1-IPPK Gene Fusion FISH Probe
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Catalog: |
GFFP-PTCH1/IPPK-09421 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PTCH1-IPPK Gene Fusion FISH Probecan detect the fusion of PTCH1 and IPPK genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PTCH1-IPPK Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Patched 1 |
Gene Summary 1 |
This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017] |
Chromosome 1 |
Chromosome 9 |
Locus 1 |
9q22.32 |
Coordinates 1 |
This gene maps to 98205263-98279247 in GRCh37 coordinates. |
Gene Name 2 |
Inositol-pentakisphosphate 2-kinase |
Gene Summary 2 |
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q22.31 |
Coordinates 2 |
This gene maps to 95375465-95432547 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PTCH1/IPPK-09421-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PTCH1/IPPK-09421-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PTCH1/IPPK-09421-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PTCH1/IPPK-09421-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PTCH1/IPPK-09421-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PTCH1/IPPK-09421-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PTCH1/IPPK-09421-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PTCH1/IPPK-09421-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PTCH1/IPPK-09421-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PTCH1/IPPK-09421-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PTCH1/IPPK-09421-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PTCH1/IPPK-09421-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PTCH1/IPPK-09421-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PTCH1/IPPK-09421-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PTCH1/IPPK-09421-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PTCH1/IPPK-09421-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PTCH1/IPPK-09421-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PTCH1/IPPK-09421-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PTCH1/IPPK-09421-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PTCH1/IPPK-09421-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PTCH1/IPPK-09421-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PTCH1/IPPK-09421-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PTCH1/IPPK-09421-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PTCH1/IPPK-09421-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PTCH1/IPPK-09421-AQAQ |
467nm;467nm |
418nm;418nm |
|
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