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PSMD3-UNC45B Gene Fusion FISH Probe

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Catalog: GFFP-PSMD3/UNC45B-09437
Classification: Gene Fusion FISH Probes
Description: The PSMD3-UNC45B Gene Fusion FISH Probecan detect the fusion of PSMD3 and UNC45B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PSMD3-UNC45B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Proteasome 26S Subunit, Non-ATPase 3
Gene Summary 1 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]
Chromosome 1 Chromosome 17
Locus 1 17q21.1
Coordinates 1 This gene maps to 38137059-38154212 in GRCh37 coordinates.
Gene Name 2 Unc-45 Myosin Chaperone B
Gene Summary 2 This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Chromosome 2 Chromosome17
Locus 2 17q12
Coordinates 2 This gene maps to 33474835-33516364 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PSMD3/UNC45B-09437-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PSMD3/UNC45B-09437-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PSMD3/UNC45B-09437-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PSMD3/UNC45B-09437-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PSMD3/UNC45B-09437-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PSMD3/UNC45B-09437-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PSMD3/UNC45B-09437-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PSMD3/UNC45B-09437-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PSMD3/UNC45B-09437-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PSMD3/UNC45B-09437-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PSMD3/UNC45B-09437-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PSMD3/UNC45B-09437-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PSMD3/UNC45B-09437-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PSMD3/UNC45B-09437-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PSMD3/UNC45B-09437-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PSMD3/UNC45B-09437-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PSMD3/UNC45B-09437-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PSMD3/UNC45B-09437-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PSMD3/UNC45B-09437-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PSMD3/UNC45B-09437-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PSMD3/UNC45B-09437-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PSMD3/UNC45B-09437-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PSMD3/UNC45B-09437-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PSMD3/UNC45B-09437-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PSMD3/UNC45B-09437-AQAQ 467nm;467nm 418nm;418nm

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