PSMD3-UNC45B Gene Fusion FISH Probe
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Catalog: |
GFFP-PSMD3/UNC45B-09437 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PSMD3-UNC45B Gene Fusion FISH Probecan detect the fusion of PSMD3 and UNC45B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PSMD3-UNC45B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Proteasome 26S Subunit, Non-ATPase 3 |
Gene Summary 1 |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.1 |
Coordinates 1 |
This gene maps to 38137059-38154212 in GRCh37 coordinates. |
Gene Name 2 |
Unc-45 Myosin Chaperone B |
Gene Summary 2 |
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q12 |
Coordinates 2 |
This gene maps to 33474835-33516364 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PSMD3/UNC45B-09437-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PSMD3/UNC45B-09437-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PSMD3/UNC45B-09437-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PSMD3/UNC45B-09437-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PSMD3/UNC45B-09437-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PSMD3/UNC45B-09437-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PSMD3/UNC45B-09437-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PSMD3/UNC45B-09437-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PSMD3/UNC45B-09437-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PSMD3/UNC45B-09437-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PSMD3/UNC45B-09437-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PSMD3/UNC45B-09437-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PSMD3/UNC45B-09437-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PSMD3/UNC45B-09437-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PSMD3/UNC45B-09437-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PSMD3/UNC45B-09437-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PSMD3/UNC45B-09437-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PSMD3/UNC45B-09437-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PSMD3/UNC45B-09437-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PSMD3/UNC45B-09437-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PSMD3/UNC45B-09437-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PSMD3/UNC45B-09437-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PSMD3/UNC45B-09437-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PSMD3/UNC45B-09437-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PSMD3/UNC45B-09437-AQAQ |
467nm;467nm |
418nm;418nm |
|
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