PSAP-DDX27 Gene Fusion FISH Probe
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Catalog: |
GFFP-PSAP/DDX27-09472 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PSAP-DDX27 Gene Fusion FISH Probecan detect the fusion of PSAP and DDX27 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PSAP-DDX27 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Prosaposin |
Gene Summary 1 |
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10q22.1 |
Coordinates 1 |
This gene maps to 73576054-73611082 in GRCh37 coordinates. |
Gene Name 2 |
DEAD-box Helicase 27 |
Gene Summary 2 |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.13 |
Coordinates 2 |
This gene maps to 47835831-47860614 in GRCh37 coordinates. |
Associated Diseases |
Uveal Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PSAP/DDX27-09472-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PSAP/DDX27-09472-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PSAP/DDX27-09472-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PSAP/DDX27-09472-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PSAP/DDX27-09472-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PSAP/DDX27-09472-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PSAP/DDX27-09472-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PSAP/DDX27-09472-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PSAP/DDX27-09472-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PSAP/DDX27-09472-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PSAP/DDX27-09472-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PSAP/DDX27-09472-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PSAP/DDX27-09472-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PSAP/DDX27-09472-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PSAP/DDX27-09472-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PSAP/DDX27-09472-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PSAP/DDX27-09472-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PSAP/DDX27-09472-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PSAP/DDX27-09472-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PSAP/DDX27-09472-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PSAP/DDX27-09472-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PSAP/DDX27-09472-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PSAP/DDX27-09472-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PSAP/DDX27-09472-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PSAP/DDX27-09472-AQAQ |
467nm;467nm |
418nm;418nm |
|
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