PRR5-ARHGAP8-XRCC6 Gene Fusion FISH Probe
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Catalog: |
GFFP-PRR5/ARHGAP8/XRCC6-09494 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PRR5-ARHGAP8-XRCC6 Gene Fusion FISH Probecan detect the fusion of PRR5-ARHGAP8 and XRCC6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PRR5-ARHGAP8-XRCC6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
X-ray Repair Cross Complementing 6 |
Gene Summary 1 |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 22 |
Locus 1 |
22q13.2 |
Coordinates 1 |
This gene maps to 42017294-42060052 in GRCh37 coordinates. |
Gene Name 2 |
PRR5-ARHGAP8 Readthrough |
Gene Summary 2 |
The PRR5-ARHGAP8 mRNA is an infrequent but naturally occurring read-through transcript of the neighboring proline rich 5, renal (PRR5) and Rho GTPase activating protein 8 (ARHGAP8) genes. The resulting fusion protein contains sequence identity with each individual gene product, and it includes domains characteristic of a RhoGAP protein. The significance of this read-through transcript and the function of its protein product have not yet been determined. [provided by RefSeq, Nov 2010] |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q13.31 |
Coordinates 2 |
This gene maps to 45098381-45258664 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PRR5/ARHGAP8/XRCC6-09494-AQAQ |
467nm;467nm |
418nm;418nm |
|
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