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PRMT1-TLE6 Gene Fusion FISH Probe

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Catalog: GFFP-PRMT1/TLE6-09525
Classification: Gene Fusion FISH Probes
Description: The PRMT1-TLE6 Gene Fusion FISH Probecan detect the fusion of PRMT1 and TLE6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PRMT1-TLE6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Arginine Methyltransferase 1
Gene Summary 1 This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
Chromosome 1 Chromosome 19
Locus 1 19q13.33
Coordinates 1 This gene maps to 50180408-50191704 in GRCh37 coordinates.
Gene Name 2 Transducin Like Enhancer Of Split 6
Gene Summary 2 This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Chromosome 2 Chromosome19
Locus 2 19p13.3
Coordinates 2 This gene maps to 2977535-2995182 in GRCh37 coordinates.
Associated Diseases Acute Myeloid Leukemia
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PRMT1/TLE6-09525-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PRMT1/TLE6-09525-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PRMT1/TLE6-09525-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PRMT1/TLE6-09525-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PRMT1/TLE6-09525-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PRMT1/TLE6-09525-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PRMT1/TLE6-09525-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PRMT1/TLE6-09525-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PRMT1/TLE6-09525-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PRMT1/TLE6-09525-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PRMT1/TLE6-09525-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PRMT1/TLE6-09525-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PRMT1/TLE6-09525-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PRMT1/TLE6-09525-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PRMT1/TLE6-09525-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PRMT1/TLE6-09525-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PRMT1/TLE6-09525-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PRMT1/TLE6-09525-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PRMT1/TLE6-09525-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PRMT1/TLE6-09525-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PRMT1/TLE6-09525-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PRMT1/TLE6-09525-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PRMT1/TLE6-09525-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PRMT1/TLE6-09525-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PRMT1/TLE6-09525-AQAQ 467nm;467nm 418nm;418nm

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