PRKCZ-GABRD Gene Fusion FISH Probe
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Catalog: |
GFFP-PRKCZ/GABRD-09199 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PRKCZ-GABRD Gene Fusion FISH Probecan detect the fusion of PRKCZ and GABRD genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PRKCZ-GABRD Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Gamma-aminobutyric Acid Type A Receptor Delta Subunit |
Gene Summary 1 |
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1p36.33 |
Coordinates 1 |
This gene maps to 1950767-1962192 in GRCh37 coordinates. |
Gene Name 2 |
Protein Kinase C Zeta |
Gene Summary 2 |
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p36.33 |
Coordinates 2 |
This gene maps to 1981908-2116834 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PRKCZ/GABRD-09199-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PRKCZ/GABRD-09199-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PRKCZ/GABRD-09199-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PRKCZ/GABRD-09199-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PRKCZ/GABRD-09199-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PRKCZ/GABRD-09199-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PRKCZ/GABRD-09199-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PRKCZ/GABRD-09199-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PRKCZ/GABRD-09199-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PRKCZ/GABRD-09199-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PRKCZ/GABRD-09199-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PRKCZ/GABRD-09199-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PRKCZ/GABRD-09199-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PRKCZ/GABRD-09199-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PRKCZ/GABRD-09199-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PRKCZ/GABRD-09199-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PRKCZ/GABRD-09199-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PRKCZ/GABRD-09199-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PRKCZ/GABRD-09199-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PRKCZ/GABRD-09199-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PRKCZ/GABRD-09199-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PRKCZ/GABRD-09199-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PRKCZ/GABRD-09199-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PRKCZ/GABRD-09199-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PRKCZ/GABRD-09199-AQAQ |
467nm;467nm |
418nm;418nm |
|
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