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PRKAR2A-CACNA2D3 Gene Fusion FISH Probe

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Catalog: GFFP-PRKAR2A/CACNA2D3-09213
Classification: Gene Fusion FISH Probes
Description: The PRKAR2A-CACNA2D3 Gene Fusion FISH Probecan detect the fusion of PRKAR2A and CACNA2D3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PRKAR2A-CACNA2D3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Kinase CAMP-dependent Type II Regulatory Subunit Alpha
Gene Summary 1 cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 3
Locus 1 3p21.31
Coordinates 1 This gene maps to 48788092-48885270 in GRCh37 coordinates.
Gene Name 2 Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 3
Gene Summary 2 This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome3
Locus 2 3p21.1-p14.3
Coordinates 2 This gene maps to 54156692-55108584 in GRCh37 coordinates.
Associated Diseases Thymoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PRKAR2A/CACNA2D3-09213-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PRKAR2A/CACNA2D3-09213-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PRKAR2A/CACNA2D3-09213-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PRKAR2A/CACNA2D3-09213-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PRKAR2A/CACNA2D3-09213-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PRKAR2A/CACNA2D3-09213-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PRKAR2A/CACNA2D3-09213-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PRKAR2A/CACNA2D3-09213-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PRKAR2A/CACNA2D3-09213-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PRKAR2A/CACNA2D3-09213-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PRKAR2A/CACNA2D3-09213-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PRKAR2A/CACNA2D3-09213-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PRKAR2A/CACNA2D3-09213-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PRKAR2A/CACNA2D3-09213-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PRKAR2A/CACNA2D3-09213-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PRKAR2A/CACNA2D3-09213-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PRKAR2A/CACNA2D3-09213-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PRKAR2A/CACNA2D3-09213-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PRKAR2A/CACNA2D3-09213-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PRKAR2A/CACNA2D3-09213-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PRKAR2A/CACNA2D3-09213-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PRKAR2A/CACNA2D3-09213-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PRKAR2A/CACNA2D3-09213-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PRKAR2A/CACNA2D3-09213-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PRKAR2A/CACNA2D3-09213-AQAQ 467nm;467nm 418nm;418nm

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