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PRKAR1A-PITPNC1 Gene Fusion FISH Probe

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Catalog: GFFP-PRKAR1A/PITPNC1-09215
Classification: Gene Fusion FISH Probes
Description: The PRKAR1A-PITPNC1 Gene Fusion FISH Probecan detect the fusion of PRKAR1A and PITPNC1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PRKAR1A-PITPNC1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Kinase CAMP-dependent Type I Regulatory Subunit Alpha
Gene Summary 1 cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. [provided by RefSeq, Jan 2013]
Chromosome 1 Chromosome 17
Locus 1 17q24.2
Coordinates 1 This gene maps to 66508109-66528910 in GRCh37 coordinates.
Gene Name 2 Phosphatidylinositol Transfer Protein, Cytoplasmic 1
Gene Summary 2 This gene encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol between membrane compartments. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, May 2012]
Chromosome 2 Chromosome17
Locus 2 17q24.2
Coordinates 2 This gene maps to 65373923-65689647 in GRCh37 coordinates.
Associated Diseases Colon Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PRKAR1A/PITPNC1-09215-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PRKAR1A/PITPNC1-09215-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PRKAR1A/PITPNC1-09215-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PRKAR1A/PITPNC1-09215-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PRKAR1A/PITPNC1-09215-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PRKAR1A/PITPNC1-09215-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PRKAR1A/PITPNC1-09215-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PRKAR1A/PITPNC1-09215-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PRKAR1A/PITPNC1-09215-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PRKAR1A/PITPNC1-09215-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PRKAR1A/PITPNC1-09215-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PRKAR1A/PITPNC1-09215-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PRKAR1A/PITPNC1-09215-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PRKAR1A/PITPNC1-09215-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PRKAR1A/PITPNC1-09215-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PRKAR1A/PITPNC1-09215-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PRKAR1A/PITPNC1-09215-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PRKAR1A/PITPNC1-09215-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PRKAR1A/PITPNC1-09215-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PRKAR1A/PITPNC1-09215-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PRKAR1A/PITPNC1-09215-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PRKAR1A/PITPNC1-09215-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PRKAR1A/PITPNC1-09215-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PRKAR1A/PITPNC1-09215-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PRKAR1A/PITPNC1-09215-AQAQ 467nm;467nm 418nm;418nm

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