PRAME-ACO2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PRAME/ACO2-09235 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PRAME-ACO2 Gene Fusion FISH Probecan detect the fusion of PRAME and ACO2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PRAME-ACO2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Aconitase 2 |
Gene Summary 1 |
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 22 |
Locus 1 |
22q13.2 |
Coordinates 1 |
This gene maps to 41865128-41924993 in GRCh37 coordinates. |
Gene Name 2 |
Preferentially Expressed Antigen In Melanoma |
Gene Summary 2 |
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q11.22 |
Coordinates 2 |
This gene maps to 22890122-22901696 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-PRAME/ACO2-09235-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PRAME/ACO2-09235-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PRAME/ACO2-09235-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PRAME/ACO2-09235-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PRAME/ACO2-09235-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PRAME/ACO2-09235-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PRAME/ACO2-09235-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PRAME/ACO2-09235-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PRAME/ACO2-09235-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PRAME/ACO2-09235-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PRAME/ACO2-09235-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PRAME/ACO2-09235-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PRAME/ACO2-09235-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PRAME/ACO2-09235-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PRAME/ACO2-09235-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PRAME/ACO2-09235-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PRAME/ACO2-09235-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PRAME/ACO2-09235-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PRAME/ACO2-09235-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PRAME/ACO2-09235-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PRAME/ACO2-09235-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PRAME/ACO2-09235-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PRAME/ACO2-09235-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PRAME/ACO2-09235-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PRAME/ACO2-09235-AQAQ |
467nm;467nm |
418nm;418nm |
|
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