PPM1A-ADCK4 Gene Fusion FISH Probe
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Catalog: |
GFFP-PPM1A/ADCK4-09008 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PPM1A-ADCK4 Gene Fusion FISH Probecan detect the fusion of PPM1A and ADCK4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PPM1A-ADCK4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Protein Phosphatase, Mg2+/Mn2+ Dependent 1A |
Gene Summary 1 |
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q23.1 |
Coordinates 1 |
This gene maps to 60712469-60765805 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PPM1A/ADCK4-09008-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PPM1A/ADCK4-09008-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PPM1A/ADCK4-09008-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PPM1A/ADCK4-09008-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PPM1A/ADCK4-09008-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PPM1A/ADCK4-09008-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PPM1A/ADCK4-09008-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PPM1A/ADCK4-09008-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PPM1A/ADCK4-09008-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PPM1A/ADCK4-09008-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PPM1A/ADCK4-09008-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PPM1A/ADCK4-09008-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PPM1A/ADCK4-09008-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PPM1A/ADCK4-09008-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PPM1A/ADCK4-09008-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PPM1A/ADCK4-09008-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PPM1A/ADCK4-09008-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PPM1A/ADCK4-09008-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PPM1A/ADCK4-09008-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PPM1A/ADCK4-09008-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PPM1A/ADCK4-09008-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PPM1A/ADCK4-09008-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PPM1A/ADCK4-09008-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PPM1A/ADCK4-09008-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PPM1A/ADCK4-09008-AQAQ |
467nm;467nm |
418nm;418nm |
|
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