PPFIA1-RBM14 Gene Fusion FISH Probe
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Catalog: |
GFFP-PPFIA1/RBM14-14442 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PPFIA1-RBM14 Gene Fusion FISH Probecan detect the fusion of PPFIA1 and RBM14 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PPFIA1-RBM14 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
PTPRF Interacting Protein Alpha 1 |
Gene Summary 1 |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.3 |
Coordinates 1 |
This gene maps to 70116822-70230502 in GRCh37 coordinates. |
Gene Name 2 |
RNA Binding Motif Protein 14 |
Gene Summary 2 |
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.2 |
Coordinates 2 |
This gene maps to 66384052-66397397 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PPFIA1/RBM14-14442-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PPFIA1/RBM14-14442-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PPFIA1/RBM14-14442-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PPFIA1/RBM14-14442-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PPFIA1/RBM14-14442-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PPFIA1/RBM14-14442-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PPFIA1/RBM14-14442-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PPFIA1/RBM14-14442-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PPFIA1/RBM14-14442-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PPFIA1/RBM14-14442-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PPFIA1/RBM14-14442-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PPFIA1/RBM14-14442-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PPFIA1/RBM14-14442-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PPFIA1/RBM14-14442-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PPFIA1/RBM14-14442-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PPFIA1/RBM14-14442-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PPFIA1/RBM14-14442-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PPFIA1/RBM14-14442-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PPFIA1/RBM14-14442-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PPFIA1/RBM14-14442-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PPFIA1/RBM14-14442-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PPFIA1/RBM14-14442-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PPFIA1/RBM14-14442-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PPFIA1/RBM14-14442-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PPFIA1/RBM14-14442-AQAQ |
467nm;467nm |
418nm;418nm |
|
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