PPFIA1-MARK2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PPFIA1/MARK2-09040 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PPFIA1-MARK2 Gene Fusion FISH Probecan detect the fusion of PPFIA1 and MARK2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PPFIA1-MARK2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Microtubule Affinity Regulating Kinase 2 |
Gene Summary 1 |
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.1 |
Coordinates 1 |
This gene maps to 63606399-63678492 in GRCh37 coordinates. |
Gene Name 2 |
PTPRF Interacting Protein Alpha 1 |
Gene Summary 2 |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.3 |
Coordinates 2 |
This gene maps to 70116822-70230502 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PPFIA1/MARK2-09040-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PPFIA1/MARK2-09040-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PPFIA1/MARK2-09040-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PPFIA1/MARK2-09040-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PPFIA1/MARK2-09040-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PPFIA1/MARK2-09040-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PPFIA1/MARK2-09040-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PPFIA1/MARK2-09040-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PPFIA1/MARK2-09040-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PPFIA1/MARK2-09040-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PPFIA1/MARK2-09040-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PPFIA1/MARK2-09040-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PPFIA1/MARK2-09040-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PPFIA1/MARK2-09040-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PPFIA1/MARK2-09040-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PPFIA1/MARK2-09040-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PPFIA1/MARK2-09040-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PPFIA1/MARK2-09040-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PPFIA1/MARK2-09040-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PPFIA1/MARK2-09040-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PPFIA1/MARK2-09040-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PPFIA1/MARK2-09040-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PPFIA1/MARK2-09040-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PPFIA1/MARK2-09040-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PPFIA1/MARK2-09040-AQAQ |
467nm;467nm |
418nm;418nm |
|
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