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PPFIA1-CBLB Gene Fusion FISH Probe

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Catalog: GFFP-PPFIA1/CBLB-09050
Classification: Gene Fusion FISH Probes
Description: The PPFIA1-CBLB Gene Fusion FISH Probecan detect the fusion of PPFIA1 and CBLB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PPFIA1-CBLB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Cbl Proto-oncogene B
Gene Summary 1 This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
Chromosome 1 Chromosome 3
Locus 1 3q13.11
Coordinates 1 This gene maps to 105377108-105587887 in GRCh37 coordinates.
Gene Name 2 PTPRF Interacting Protein Alpha 1
Gene Summary 2 The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome11
Locus 2 11q13.3
Coordinates 2 This gene maps to 70116822-70230502 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PPFIA1/CBLB-09050-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PPFIA1/CBLB-09050-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PPFIA1/CBLB-09050-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PPFIA1/CBLB-09050-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PPFIA1/CBLB-09050-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PPFIA1/CBLB-09050-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PPFIA1/CBLB-09050-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PPFIA1/CBLB-09050-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PPFIA1/CBLB-09050-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PPFIA1/CBLB-09050-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PPFIA1/CBLB-09050-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PPFIA1/CBLB-09050-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PPFIA1/CBLB-09050-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PPFIA1/CBLB-09050-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PPFIA1/CBLB-09050-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PPFIA1/CBLB-09050-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PPFIA1/CBLB-09050-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PPFIA1/CBLB-09050-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PPFIA1/CBLB-09050-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PPFIA1/CBLB-09050-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PPFIA1/CBLB-09050-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PPFIA1/CBLB-09050-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PPFIA1/CBLB-09050-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PPFIA1/CBLB-09050-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PPFIA1/CBLB-09050-AQAQ 467nm;467nm 418nm;418nm

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