POLK-HSD17B4 Gene Fusion FISH Probe
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Catalog: |
GFFP-POLK/HSD17B4-09101 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The POLK-HSD17B4 Gene Fusion FISH Probecan detect the fusion of POLK and HSD17B4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
POLK-HSD17B4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Hydroxysteroid 17-beta Dehydrogenase 4 |
Gene Summary 1 |
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5q23.1 |
Coordinates 1 |
This gene maps to 118788137-118878030 in GRCh37 coordinates. |
Gene Name 2 |
DNA Polymerase Kappa |
Gene Summary 2 |
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5q13.3 |
Coordinates 2 |
This gene maps to 74807656-74895646 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-POLK/HSD17B4-09101-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-POLK/HSD17B4-09101-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-POLK/HSD17B4-09101-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-POLK/HSD17B4-09101-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-POLK/HSD17B4-09101-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-POLK/HSD17B4-09101-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-POLK/HSD17B4-09101-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-POLK/HSD17B4-09101-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-POLK/HSD17B4-09101-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-POLK/HSD17B4-09101-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-POLK/HSD17B4-09101-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-POLK/HSD17B4-09101-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-POLK/HSD17B4-09101-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-POLK/HSD17B4-09101-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-POLK/HSD17B4-09101-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-POLK/HSD17B4-09101-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-POLK/HSD17B4-09101-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-POLK/HSD17B4-09101-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-POLK/HSD17B4-09101-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-POLK/HSD17B4-09101-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-POLK/HSD17B4-09101-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-POLK/HSD17B4-09101-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-POLK/HSD17B4-09101-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-POLK/HSD17B4-09101-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-POLK/HSD17B4-09101-AQAQ |
467nm;467nm |
418nm;418nm |
|
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