POLG-CGNL1 Gene Fusion FISH Probe
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Catalog: |
GFFP-POLG/CGNL1-09102 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The POLG-CGNL1 Gene Fusion FISH Probecan detect the fusion of POLG and CGNL1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
POLG-CGNL1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DNA Polymerase Gamma, Catalytic Subunit |
Gene Summary 1 |
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q26.1 |
Coordinates 1 |
This gene maps to 89859535-89878026 in GRCh37 coordinates. |
Gene Name 2 |
Cingulin Like 1 |
Gene Summary 2 |
This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q21.3 |
Coordinates 2 |
This gene maps to 57668704-57842921 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-POLG/CGNL1-09102-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-POLG/CGNL1-09102-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-POLG/CGNL1-09102-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-POLG/CGNL1-09102-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-POLG/CGNL1-09102-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-POLG/CGNL1-09102-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-POLG/CGNL1-09102-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-POLG/CGNL1-09102-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-POLG/CGNL1-09102-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-POLG/CGNL1-09102-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-POLG/CGNL1-09102-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-POLG/CGNL1-09102-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-POLG/CGNL1-09102-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-POLG/CGNL1-09102-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-POLG/CGNL1-09102-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-POLG/CGNL1-09102-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-POLG/CGNL1-09102-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-POLG/CGNL1-09102-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-POLG/CGNL1-09102-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-POLG/CGNL1-09102-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-POLG/CGNL1-09102-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-POLG/CGNL1-09102-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-POLG/CGNL1-09102-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-POLG/CGNL1-09102-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-POLG/CGNL1-09102-AQAQ |
467nm;467nm |
418nm;418nm |
|
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