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PMM2-ABAT Gene Fusion FISH Probe

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Catalog: GFFP-PMM2/ABAT-09138
Classification: Gene Fusion FISH Probes
Description: The PMM2-ABAT Gene Fusion FISH Probecan detect the fusion of PMM2 and ABAT genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PMM2-ABAT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 4-aminobutyrate Aminotransferase
Gene Summary 1 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 16
Locus 1 16p13.2
Coordinates 1 This gene maps to 8768443-8878432 in GRCh37 coordinates.
Gene Name 2 Phosphomannomutase 2
Gene Summary 2 The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome16
Locus 2 16p13.2
Coordinates 2 This gene maps to 8891669-8943194 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PMM2/ABAT-09138-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PMM2/ABAT-09138-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PMM2/ABAT-09138-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PMM2/ABAT-09138-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PMM2/ABAT-09138-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PMM2/ABAT-09138-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PMM2/ABAT-09138-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PMM2/ABAT-09138-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PMM2/ABAT-09138-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PMM2/ABAT-09138-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PMM2/ABAT-09138-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PMM2/ABAT-09138-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PMM2/ABAT-09138-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PMM2/ABAT-09138-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PMM2/ABAT-09138-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PMM2/ABAT-09138-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PMM2/ABAT-09138-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PMM2/ABAT-09138-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PMM2/ABAT-09138-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PMM2/ABAT-09138-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PMM2/ABAT-09138-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PMM2/ABAT-09138-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PMM2/ABAT-09138-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PMM2/ABAT-09138-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PMM2/ABAT-09138-AQAQ 467nm;467nm 418nm;418nm

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