PLEKHA7-ABCC8 Gene Fusion FISH Probe
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Catalog: |
GFFP-PLEKHA7/ABCC8-08876 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PLEKHA7-ABCC8 Gene Fusion FISH Probecan detect the fusion of PLEKHA7 and ABCC8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PLEKHA7-ABCC8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ATP Binding Cassette Subfamily C Member 8 |
Gene Summary 1 |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11p15.1 |
Coordinates 1 |
This gene maps to 17414431-17498449 in GRCh37 coordinates. |
Gene Name 2 |
Pleckstrin Homology Domain Containing A7 |
Gene Summary 2 |
The Pleckstrin Homology Domain Containing A7 (PLEKHA7) gene is located on chr11 :16809206-17035963 at 11p15.2-p15.1. |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11p15.2-p15.1 |
Coordinates 2 |
This gene maps to 16809206-17035963 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PLEKHA7/ABCC8-08876-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PLEKHA7/ABCC8-08876-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PLEKHA7/ABCC8-08876-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PLEKHA7/ABCC8-08876-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PLEKHA7/ABCC8-08876-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PLEKHA7/ABCC8-08876-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PLEKHA7/ABCC8-08876-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PLEKHA7/ABCC8-08876-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PLEKHA7/ABCC8-08876-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PLEKHA7/ABCC8-08876-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PLEKHA7/ABCC8-08876-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PLEKHA7/ABCC8-08876-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PLEKHA7/ABCC8-08876-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PLEKHA7/ABCC8-08876-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PLEKHA7/ABCC8-08876-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PLEKHA7/ABCC8-08876-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PLEKHA7/ABCC8-08876-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PLEKHA7/ABCC8-08876-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PLEKHA7/ABCC8-08876-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PLEKHA7/ABCC8-08876-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PLEKHA7/ABCC8-08876-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PLEKHA7/ABCC8-08876-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PLEKHA7/ABCC8-08876-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PLEKHA7/ABCC8-08876-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PLEKHA7/ABCC8-08876-AQAQ |
467nm;467nm |
418nm;418nm |
|
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