PLCB4-BMP2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PLCB4/BMP2-08913 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PLCB4-BMP2 Gene Fusion FISH Probecan detect the fusion of PLCB4 and BMP2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PLCB4-BMP2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Bone Morphogenetic Protein 2 |
Gene Summary 1 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] |
Chromosome 1 |
Chromosome 20 |
Locus 1 |
20p12.3 |
Coordinates 1 |
This gene maps to 6748744-6760910 in GRCh37 coordinates. |
Gene Name 2 |
Phospholipase C Beta 4 |
Gene Summary 2 |
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20p12.3-p12.2 |
Coordinates 2 |
This gene maps to 9049700-9461462 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PLCB4/BMP2-08913-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PLCB4/BMP2-08913-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PLCB4/BMP2-08913-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PLCB4/BMP2-08913-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PLCB4/BMP2-08913-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PLCB4/BMP2-08913-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PLCB4/BMP2-08913-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PLCB4/BMP2-08913-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PLCB4/BMP2-08913-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PLCB4/BMP2-08913-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PLCB4/BMP2-08913-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PLCB4/BMP2-08913-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PLCB4/BMP2-08913-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PLCB4/BMP2-08913-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PLCB4/BMP2-08913-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PLCB4/BMP2-08913-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PLCB4/BMP2-08913-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PLCB4/BMP2-08913-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PLCB4/BMP2-08913-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PLCB4/BMP2-08913-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PLCB4/BMP2-08913-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PLCB4/BMP2-08913-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PLCB4/BMP2-08913-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PLCB4/BMP2-08913-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PLCB4/BMP2-08913-AQAQ |
467nm;467nm |
418nm;418nm |
|
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