PIP5K1C-MATK Gene Fusion FISH Probe
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Catalog: |
GFFP-PIP5K1C/MATK-14435 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PIP5K1C-MATK Gene Fusion FISH Probecan detect the fusion of PIP5K1C and MATK genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PIP5K1C-MATK Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Megakaryocyte-associated Tyrosine Kinase |
Gene Summary 1 |
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.3 |
Coordinates 1 |
This gene maps to 3777966-3801810 in GRCh37 coordinates. |
Gene Name 2 |
Phosphatidylinositol-4-phosphate 5-kinase Type 1 Gamma |
Gene Summary 2 |
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.3 |
Coordinates 2 |
This gene maps to 3630178-3700477 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PIP5K1C/MATK-14435-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PIP5K1C/MATK-14435-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PIP5K1C/MATK-14435-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PIP5K1C/MATK-14435-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PIP5K1C/MATK-14435-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PIP5K1C/MATK-14435-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PIP5K1C/MATK-14435-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PIP5K1C/MATK-14435-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PIP5K1C/MATK-14435-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PIP5K1C/MATK-14435-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PIP5K1C/MATK-14435-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PIP5K1C/MATK-14435-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PIP5K1C/MATK-14435-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PIP5K1C/MATK-14435-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PIP5K1C/MATK-14435-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PIP5K1C/MATK-14435-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PIP5K1C/MATK-14435-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PIP5K1C/MATK-14435-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PIP5K1C/MATK-14435-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PIP5K1C/MATK-14435-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PIP5K1C/MATK-14435-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PIP5K1C/MATK-14435-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PIP5K1C/MATK-14435-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PIP5K1C/MATK-14435-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PIP5K1C/MATK-14435-AQAQ |
467nm;467nm |
418nm;418nm |
|
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