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PIKFYVE-ZNF124 Gene Fusion FISH Probe

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Catalog: GFFP-PIKFYVE/ZNF124-08974
Classification: Gene Fusion FISH Probes
Description: The PIKFYVE-ZNF124 Gene Fusion FISH Probecan detect the fusion of PIKFYVE and ZNF124 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PIKFYVE-ZNF124 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Zinc Finger Protein 124
Gene Summary 1 This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014]
Chromosome 1 Chromosome 1
Locus 1 1q44
Coordinates 1 This gene maps to 247285276-247335318 in GRCh37 coordinates.
Gene Name 2 Phosphoinositide Kinase, FYVE-type Zinc Finger Containing
Gene Summary 2 Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD); an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
Chromosome 2 Chromosome2
Locus 2 2q34
Coordinates 2 This gene maps to 209130990-209223475 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PIKFYVE/ZNF124-08974-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PIKFYVE/ZNF124-08974-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PIKFYVE/ZNF124-08974-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PIKFYVE/ZNF124-08974-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PIKFYVE/ZNF124-08974-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PIKFYVE/ZNF124-08974-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PIKFYVE/ZNF124-08974-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PIKFYVE/ZNF124-08974-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PIKFYVE/ZNF124-08974-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PIKFYVE/ZNF124-08974-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PIKFYVE/ZNF124-08974-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PIKFYVE/ZNF124-08974-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PIKFYVE/ZNF124-08974-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PIKFYVE/ZNF124-08974-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PIKFYVE/ZNF124-08974-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PIKFYVE/ZNF124-08974-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PIKFYVE/ZNF124-08974-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PIKFYVE/ZNF124-08974-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PIKFYVE/ZNF124-08974-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PIKFYVE/ZNF124-08974-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PIKFYVE/ZNF124-08974-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PIKFYVE/ZNF124-08974-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PIKFYVE/ZNF124-08974-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PIKFYVE/ZNF124-08974-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PIKFYVE/ZNF124-08974-AQAQ 467nm;467nm 418nm;418nm

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