PICALM-ME3 Gene Fusion FISH Probe
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Catalog: |
GFFP-PICALM/ME3-08690 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PICALM-ME3 Gene Fusion FISH Probecan detect the fusion of PICALM and ME3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PICALM-ME3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Phosphatidylinositol Binding Clathrin Assembly Protein |
Gene Summary 1 |
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q14.2 |
Coordinates 1 |
This gene maps to 85668213-85780923 in GRCh37 coordinates. |
Gene Name 2 |
Malic Enzyme 3 |
Gene Summary 2 |
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q14.2 |
Coordinates 2 |
This gene maps to 86152149-86383678 in GRCh37 coordinates. |
Associated Diseases |
Ovarian Serous Cystadenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PICALM/ME3-08690-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PICALM/ME3-08690-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PICALM/ME3-08690-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PICALM/ME3-08690-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PICALM/ME3-08690-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PICALM/ME3-08690-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PICALM/ME3-08690-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PICALM/ME3-08690-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PICALM/ME3-08690-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PICALM/ME3-08690-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PICALM/ME3-08690-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PICALM/ME3-08690-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PICALM/ME3-08690-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PICALM/ME3-08690-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PICALM/ME3-08690-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PICALM/ME3-08690-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PICALM/ME3-08690-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PICALM/ME3-08690-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PICALM/ME3-08690-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PICALM/ME3-08690-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PICALM/ME3-08690-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PICALM/ME3-08690-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PICALM/ME3-08690-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PICALM/ME3-08690-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PICALM/ME3-08690-AQAQ |
467nm;467nm |
418nm;418nm |
|
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