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PHLPP1-WDR12 Gene Fusion FISH Probe

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Catalog: GFFP-PHLPP1/WDR12-08718
Classification: Gene Fusion FISH Probes
Description: The PHLPP1-WDR12 Gene Fusion FISH Probecan detect the fusion of PHLPP1 and WDR12 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PHLPP1-WDR12 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 PH Domain And Leucine Rich Repeat Protein Phosphatase 1
Gene Summary 1 This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Chromosome 1 Chromosome 18
Locus 1 18q21.33
Coordinates 1 This gene maps to 60382671-60647666 in GRCh37 coordinates.
Gene Name 2 WD Repeat Domain 12
Gene Summary 2 This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.[provided by RefSeq, Dec 2008]
Chromosome 2 Chromosome2
Locus 2 2q33.2
Coordinates 2 This gene maps to 203745322-203776949 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PHLPP1/WDR12-08718-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PHLPP1/WDR12-08718-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PHLPP1/WDR12-08718-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PHLPP1/WDR12-08718-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PHLPP1/WDR12-08718-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PHLPP1/WDR12-08718-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PHLPP1/WDR12-08718-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PHLPP1/WDR12-08718-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PHLPP1/WDR12-08718-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PHLPP1/WDR12-08718-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PHLPP1/WDR12-08718-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PHLPP1/WDR12-08718-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PHLPP1/WDR12-08718-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PHLPP1/WDR12-08718-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PHLPP1/WDR12-08718-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PHLPP1/WDR12-08718-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PHLPP1/WDR12-08718-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PHLPP1/WDR12-08718-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PHLPP1/WDR12-08718-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PHLPP1/WDR12-08718-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PHLPP1/WDR12-08718-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PHLPP1/WDR12-08718-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PHLPP1/WDR12-08718-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PHLPP1/WDR12-08718-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PHLPP1/WDR12-08718-AQAQ 467nm;467nm 418nm;418nm

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